Quarterly report pursuant to Section 13 or 15(d)

STOCK-BASED COMPENSATION (Details Narrative)

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STOCK-BASED COMPENSATION (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 8 Months Ended 9 Months Ended 12 Months Ended
Dec. 31, 2017
Jun. 20, 2017
Jun. 16, 2017
Mar. 01, 2017
May 27, 2016
Feb. 09, 2016
Jul. 31, 2017
May 31, 2017
Feb. 28, 2017
Jan. 31, 2017
Sep. 30, 2017
Sep. 30, 2016
Sep. 12, 2017
Sep. 30, 2017
Sep. 30, 2016
Jun. 16, 2017
May 11, 2016
Jun. 09, 2014
Stock-based compensation expense                           $ 1,477 $ 2,367      
Number of shares granted options to purchase                           260,000        
Exercise price (in dollars price per share)                           $ 4.63        
Exercisable, weighted average remaining contractual term                           6 years 9 months 11 days        
Stock Option [Member]                                    
Stock-based compensation expense                     $ 400 $ 700   $ 1,400 2,100      
Unrecognized compensation cost                     1,200     $ 1,200        
Unrecognized weighted average period                           1 year 1 month 3 days        
Restricted Stock Units [Member]                                    
Number of shares granted other than option                                  
Stock-based compensation expense                     $ 0 $ 86   $ 72 230      
Non-Employees Directors [Member]                                    
Vesting period   1 year                     1 year          
Number of shares granted options to purchase   150,000                     20,000          
Exercise price (in dollars price per share)   $ 2.73                     $ 2.78          
Exercisable, weighted average remaining contractual term   10 years                     10 years          
Employee [Member]                                    
Vesting period       1 year 1 year 1 year                        
Weighted average grant date fair value other than option (in dollars per share)       $ 3.36                            
Description of award vesting rights      

Vesting 1/3 on the first anniversary and 1/36th each month thereafter for 24 months.

                           
Number of shares granted options to purchase       61,750 3,500 40,300                        
Exercise price (in dollars price per share)       $ 5.50 $ 24.20 $ 50.30                        
Exercisable, weighted average remaining contractual term       10 years 10 years 10 years                        
Employee [Member] | Common stock [Member]                                    
Vesting period         1 year                          
Description of award vesting rights        

Vesting 1/3 each upon the Company’s common stock having an average closing sale price equal to or exceeding each of $60.00, $70.00 and $80.00 per share for 20 consecutive trading days, subject to a one year minimum service period prior to vesting.

Vesting 1/3 each upon the Company’s common stock having an average closing sale price equal to or exceeding each of $60.00, $70.00 and $80.00 per share for 20 consecutive trading days, subject to a one year minimum service period prior to vesting.

                       
Number of shares granted options to purchase         6,000 20,000                        
Exercise price (in dollars price per share)         $ 24.20 $ 50.30                        
Exercisable, weighted average remaining contractual term           10 years                        
Employee [Member] | Subsequent Event [Member]                                    
Vesting period 1 year                                  
Description of award vesting rights

Vesting 50% upon achieving enrollment of 250 participants in the ongoing HONOR study by December 31, 2017, and the remaining 50% vesting 1% for each participant that is enrolled in the HONOR study by December 31, 2017 in excess of 250, subject to a one year minimum service period prior to vesting.

                                 
Number of shares granted options to purchase 28,250                                  
Exercise price (in dollars price per share) $ 5.50                                  
Exercisable, weighted average remaining contractual term 10 years                                  
Minimum [Member] | Employee [Member]                                    
Vesting period 1 year                                  
2016 Incentive Stock Option Plan [Member]                                    
Number of shares authorized                                 278,500  
2017 Incentive Stock Option Plan [Member]                                    
Number of shares authorized     1,280,000                         1,280,000    
Description of terms of exercise price    

However, the exercise price of an incentive stock option may not be less than 110% of fair value of the common stock at the date of the grant for a 10% or more shareholder and 100% of fair value for a grantee who is not a 10% shareholder.

                             
Number of shares reserved for future issuance     1,280,000               1,153,968     1,153,968   1,280,000    
Maximum number of shares issued pursuant to stock-settled awards     750,000                         750,000    
Description of award under stock incentive plan    

(i) be granted options or SARs with respect to more than 750,000 shares of the Company’s common stock, (ii) earn more than 500,000 shares of the Company’s common stock under restricted stock awards, restricted stock unit awards, performance awards and/or other stock-based awards, or (iii) earn more than $5,000,000 under an award; provided, however, that each of these limitations shall be multiplied by two (2)

                             
Description of stock-settled awards    

The calculation shall be based on one share for every one share that was subject to an option or SAR and 1.15 shares for every one share that was subject to an award other than an option or SAR.

                             
Description of award vesting rights    

Stock options granted pursuant to the Plans typically vest 1/3rd 12 months from the date of grant and 1/36th each month thereafter for 24 months and expire ten years from the date of grant. In addition, the Company also issues performance-based options to executive officers, which options vest when the target parameters are met, subject to a one year minimum service period prior to vesting.

                             
2017 Incentive Stock Option Plan [Member] | Maximum [Member]                                    
Vesting period                               5 years    
Expiration period                               10 years    
2014 Employee Stock Purchase Plan [Member]                                    
Number of shares authorized                                   30,000
Number of shares reserved for future issuance                     1,689     1,689        
Stock-based compensation expense                           $ 36 $ 59      
Employee payroll deductions             $ 64     $ 10 $ 76     $ 76        
Number of shares issued under ESPP             17,760     2,496                
2014 Incentive Stock Option Plan [Member] | Non-Employees Directors [Member] | Restricted Stock Units [Member]                                    
Vesting period                 1 year                  
Number of shares granted other than option                 5,625         5,625        
Weighted average grant date fair value other than option (in dollars per share)                 $ 38.10                  
2014 Incentive Stock Option Plan [Member] | Non-Employees Directors 1 [Member] | Restricted Stock Units [Member]                                    
Number of shares granted other than option               5,625           4,125        
Weighted average grant date fair value other than option (in dollars per share)               $ 22.90