Annual report pursuant to Section 13 and 15(d)

SUBSEQUENT EVENTS (Details Narrative)

v3.22.4
SUBSEQUENT EVENTS (Details Narrative) - USD ($)
2 Months Ended 12 Months Ended
Feb. 23, 2023
Feb. 02, 2023
Jan. 02, 2023
Mar. 13, 2023
Dec. 31, 2022
Dec. 31, 2021
Subsequent Event [Line Items]            
Number of options granted (in shares)         1,695,608 486,639
Exercise price of options granted (in dollars per share)         $ 12.06 $ 40.85
Share-Based Payment Arrangement, Option [Member]            
Subsequent Event [Line Items]            
Research and development costs         $ 3,000,000 $ 2,400,000
Options term         10 years  
Share-Based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche One [Member]            
Subsequent Event [Line Items]            
Vesting percentage         33.33%  
Share-Based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche Two [Member]            
Subsequent Event [Line Items]            
Vesting percentage         2.78%  
Purchase Agreement with Lincoln Park 2022 [Member]            
Subsequent Event [Line Items]            
Number of shares issued (in shares)         1,000,000  
Number of shares issued, value         $ 500,000  
Subsequent Event [Member]            
Subsequent Event [Line Items]            
Minimum bid price requirements NASDAQ     $ 1.00      
Consecutive business days for minimum bid price     10 days      
Subsequent Event [Member] | Share-Based Payment Arrangement, Option [Member]            
Subsequent Event [Line Items]            
Number of options granted (in shares) 4,394,303          
Exercise price of options granted (in dollars per share) $ 0.73          
Options term 10 years          
Subsequent Event [Member] | Share-Based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche One [Member]            
Subsequent Event [Line Items]            
Vesting percentage 33.33%          
Subsequent Event [Member] | Share-Based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche Two [Member]            
Subsequent Event [Line Items]            
Vesting percentage 2.78%          
Subsequent Event [Member] | Share-based Payment Arrangement, Option [Member]            
Subsequent Event [Line Items]            
Number of options granted (in shares) 1,327,500          
Exercise price of options granted (in dollars per share) $ 0.91          
Options term 10 years          
Subsequent Event [Member] | Share-based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche One [Member]            
Subsequent Event [Line Items]            
Vesting percentage 33.33%          
Subsequent Event [Member] | Share-based Payment Arrangement, Option [Member] | Share-Based Payment Arrangement, Tranche Two [Member]            
Subsequent Event [Line Items]            
Vesting percentage 2.78%          
Subsequent Event [Member] | Asset Purchase Agreement [Member] | Healion Bio Inc. [Member]            
Subsequent Event [Line Items]            
Consideration paid   $ 1,200,000        
Research and development costs   $ 1,200,000        
Subsequent Event [Member] | Sales Agreement with AGP [Member]            
Subsequent Event [Line Items]            
Number of shares issued (in shares)       2,100,000    
Number of shares issued, value       $ 1,400,000    
Subsequent Event [Member] | Purchase Agreement with Lincoln Park 2022 [Member]            
Subsequent Event [Line Items]            
Number of shares issued (in shares)       600,000    
Number of shares issued, value       $ 400,000    
Subsequent Event [Member] | Existing Share Repurchase Program [Member]            
Subsequent Event [Line Items]            
Number of shares repurchased (in shares)       15,700,269    
Repurchase program amount       $ 12,500,000    
Value of shares repurchased       $ 12,500,000    
Subsequent Event [Member] | Existing Share Repurchase Program [Member] | Minimum [Member]            
Subsequent Event [Line Items]            
Price of shares repurchased (in dollars per share)       $ 0.44    
Subsequent Event [Member] | Existing Share Repurchase Program [Member] | Maximum [Member]            
Subsequent Event [Line Items]            
Price of shares repurchased (in dollars per share)       $ 1.38    
Subsequent Event [Member] | New Share Repurchase Program [Member]            
Subsequent Event [Line Items]            
Number of shares repurchased (in shares)       1,000,000    
Repurchase program amount     $ 12,500,000      
Price of shares repurchased (in dollars per share)       $ 1.14    
Value of shares repurchased       $ 1,100,000