Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF OPERATIONS

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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
COSTS AND EXPENSES:      
Research and development $ 35,504 $ 18,617 $ 4,650
General and administrative 12,658 9,039 6,238
Total operating expenses 48,162 27,656 10,888
Operating Loss (48,162) (27,656) (10,888)
Interest income, net 108 40 4
NET LOSS $ (48,054) $ (27,616) $ (10,884)
Net loss per common share, basic and diluted (in dollars per share) $ (2.86) $ (2.77) $ (3.37)
Weighted average common shares outstanding, basic and diluted (in shares) 16,791,059 9,985,515 3,231,311