Annual report pursuant to Section 13 and 15(d)

SUBSEQUENT EVENT (Details Narrative)

v3.7.0.1
SUBSEQUENT EVENT (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Apr. 13, 2017
Apr. 04, 2017
Mar. 30, 2017
Mar. 17, 2017
Mar. 01, 2017
Apr. 30, 2017
Dec. 31, 2016
Dec. 31, 2015
Number of shares granted options to purchase               69,800 51,324
Exercise price (in dollars price per share)               $ 46.58 $ 60.13
Exercisable, weighted average remaining contractual term               7 years 2 months 8 days  
Reverse stock split              

1-for-10

 
Common stock, par value (in dollars per share)               $ 0.001 $ 0.001
Common stock, outstanding               (3,918,111) (1,883,167)
Common stock, authorized               15,000,000 15,000,000
Proceeds from issuance of shares               $ 20,498 $ 47,685
Subsequent Event [Member]                  
Reverse stock split        

1-for-10

       
Common stock, par value (in dollars per share)         $ 0.001        
Common stock, outstanding         41,010,720        
Number of shares sold         4,101,072   1,486,474    
Common stock, authorized         15,000,000        
Proceeds from issuance of shares             $ 9,100    
Commission on issuance of shares             $ 300    
Subsequent Event [Member] | Underwriting Agreement [Member] | Underwritten Public Offering [Member]                  
Proceeds from issuance of shares     $ 7,200            
Commission on issuance of shares     $ 600            
Sale of stock price per share     $ 0.31            
Discount on purchase of shares     7.00%            
Offering expenses     $ 300            
Subsequent Event [Member] | Underwriting Agreement [Member] | 45 Days Over-Allotment Option [Member]                  
Number of shares sold   270,000              
Proceeds from issuance of shares   $ 1,100              
Commission on issuance of shares   $ 100              
Sale of stock price per share   $ 0.31              
Subsequent Event [Member] | Underwriting Agreement [Member] | Aegis Capital Corp. [Member] | Underwritten Public Offering [Member]                  
Number of shares sold       1,800,000          
Sale of stock price per share       $ 4.45          
Subsequent Event [Member] | Underwriting Agreement [Member] | Aegis Capital Corp. [Member] | 45 Days Over-Allotment Option [Member]                  
Number of shares sold       270,000          
Subsequent Event [Member] | Employee [Member]                  
Number of shares granted options to purchase 28,250         61,750      
Exercise price (in dollars price per share) $ 5.50         $ 5.50      
Exercisable, weighted average remaining contractual term 10 years         10 years      
Description of vesting terms          

Vesting 1/3 on the first anniversary and 1/36th each month thereafter for 24 months.

     
Subsequent Event [Member] | Employee [Member] | Minimum [Member]                  
Vesting period 1 year