Annual report pursuant to Section 13 and 15(d)

Cover

v3.22.0.1
Cover - USD ($)
 12 Months Ended
Dec. 31, 2021
Mar. 14, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2021    
Current Fiscal Year End Date --12-31    
Entity File Number 001-36019    
Entity Registrant Name TONIX PHARMACEUTICALS HOLDING CORP.    
Entity Central Index Key 0001430306    
Entity Tax Identification Number 26-1434750    
Entity Incorporation, State or Country Code NV    
Entity Address, Address Line One 26 Main Street    
Entity Address, Address Line Two Suite 101    
Entity Address, City or Town Chatham    
Entity Address, State or Province NJ    
Entity Address, Postal Zip Code 07928    
City area code 862    
Local phone number 799-8599    
Title of 12(b) Security Common Stock, $0.001 par value    
Trading Symbol TNXP    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity public float     $ 384,121,940
Entity common stock, shares outstanding   533,928,624  
Auditor Name EisnerAmper LLP    
Auditor Location Iselin, New Jersey    
Auditor Firm ID 274