Tonix Pharmaceuticals Holding Corp. Annual report pursuant to Section 13 and 15(d)

WARRANTS TO PURCHASE COMMON STOCK (Details Narrative) - USD ($)	1 Months Ended	2 Months Ended	12 Months Ended
	Aug. 31, 2020	Mar. 31, 2020	Dec. 31, 2021	Dec. 31, 2020
Class of Warrant or Right [Line Items]
Proceeds from exercise of warrants			$ 2,000	$ 9,896,000
Warrant [Member]
Class of Warrant or Right [Line Items]
Number of warrants expired			5,441	2,500
Exercise price of warrants expired (in dollars per share)			$ 630	$ 0.50
Warrant One [Member]
Class of Warrant or Right [Line Items]
Number of warrants expired			474
Exercise price of warrants expired (in dollars per share)			$ 687.50
Warrants from Feb 2020 Financing [Member]
Class of Warrant or Right [Line Items]
Number of exercised warrants	2,200,000	10,800,000	3,400	13,000,000
Exercise price (in dollars per share)	$ 0.57	$ 0.57	$ 0.57	$ 0.57
Proceeds from exercise of warrants	$ 1,300,000	$ 6,200,000	$ 2,000	$ 7,500,000
Warrants from Nov 2019 Financing [Member]
Class of Warrant or Right [Line Items]
Number of exercised warrants		2,300,000		2,300,000
Exercise price (in dollars per share)		$ 0.57		$ 0.57
Proceeds from exercise of warrants		$ 1,300,000		$ 1,300,000
Warrants from Nov 2019 Financing [Member]
Class of Warrant or Right [Line Items]
Number of exercised warrants				2,300,000
Exercise price (in dollars per share)				$ 0.50
Proceeds from exercise of warrants				$ 1,200,000