Tonix Pharmaceuticals Holding Corp. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

SALE OF COMMON STOCK (Details Narrative)

SALE OF COMMON STOCK (Details Narrative) - USD ($)									1 Months Ended	3 Months Ended		12 Months Ended
SALE OF COMMON STOCK (Details Narrative) - USD ($)	Apr. 01, 2024	Dec. 20, 2023	Oct. 03, 2023	Aug. 01, 2023	Jul. 27, 2023	Aug. 16, 2022	Dec. 03, 2021	Apr. 08, 2020	Apr. 01, 2024	Apr. 01, 2024	Mar. 31, 2023	Dec. 31, 2023	Dec. 31, 2022	Jan. 25, 2024	Sep. 30, 2023	May 09, 2023	May 07, 2023	Dec. 13, 2022	Dec. 11, 2022	Aug. 05, 2022	Aug. 03, 2022
Class of Stock [Line Items]
Common stock, authorized												160,000,000	160,000,000			160,000,000	1,000,000,000	160,000,000	24,000,000	24,000,000	8,000,000
Repurchase of common stock												$ 13,965,000
2022 Share Repurchase Program [Member]
Class of Stock [Line Items]
Shares repurchased											2,512,044
Share repurchase authorized amount											$ 12,500,000
Repurchase of common stock											12,500,000
Stock repurchase agreement expense											$ 300,000
2022 Share Repurchase Program [Member] \| Minimum [Member]
Class of Stock [Line Items]
Price per share											$ 2.75
2022 Share Repurchase Program [Member] \| Maximum [Member]
Class of Stock [Line Items]
Price per share											$ 8.61
2023 Share Repurchase Program [Member]
Class of Stock [Line Items]
Shares repurchased											160,000
Share repurchase authorized amount											$ 12,500,000
Price per share											$ 7.12
Repurchase of common stock											$ 1,100,000
Subsequent Event [Member]
Class of Stock [Line Items]
Stock offering expenses	$ 500,000
Common stock, authorized														1,000,000,000
Pre-Funded Warrants [Member]
Class of Stock [Line Items]
Exercise price												$ 0.0001
Pre-Funded Warrants [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	3,900,000								3,900,000	3,900,000
Number of warrants exercised										15,043,244
Exercise price	$ 0.0001								$ 0.0001	$ 0.0001
Common Warrants Series C [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	34,823,928								34,823,928	34,823,928
Period of trading days after FDA acceptance of NDA for warrant expiration	10 days								10 days
Common Warrants Series D [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	34,823,928								34,823,928	34,823,928
Common Warrants [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	6,950,000								6,950,000	6,950,000
Exercise price	$ 0.33								$ 0.33	$ 0.33
Common Warrants Series A [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	8,900,000								8,900,000	8,900,000
Common Warrants Series B [Member] \| Subsequent Event [Member]
Class of Stock [Line Items]
Number of shares for common warrants	8,900,000								8,900,000	8,900,000
Purchase Agreement [Member]
Class of Stock [Line Items]
Number of shares issued		25,343,242
Proceeds from equity offerings		$ 30,000,000
Purchase Agreement [Member] \| Common Stock, Pre-funded Warrants and Equity Classified Common Warrants D [Member]
Class of Stock [Line Items]
Proceeds from equity offerings		7,500,000
Stock offering expenses		$ 1,400,000
Purchase Agreement [Member] \| Pre-Funded Warrants [Member]
Class of Stock [Line Items]
Number of shares for common warrants		28,710,812
Price per share		$ 0.5549
Number of warrants exercised		6,509,010										6,509,010
Exercise price		$ 0.0001
Purchase Agreement [Member] \| Common Warrants Series C [Member]
Class of Stock [Line Items]
Number of shares for common warrants		81,081,081
Proceeds from equity offerings		$ 14,400,000
Exercise price		$ 0.555
Common stock, authorized for warrant exercise		1,000,000,000
Period of trading days after approval date to become exercisable		10 days
Warrants term		2 years
Period of trading days after FDA acceptance of NDA for warrant expiration		10 days
Purchase Agreement [Member] \| Common Warrants Series D [Member]
Class of Stock [Line Items]
Number of shares for common warrants		81,081,081
Exercise price		$ 0.85
Warrants term		5 years
Purchase Agreement [Member] \| Common Warrants [Member]
Class of Stock [Line Items]
Price per share		$ 0.555
Purchase Agreement [Member] \| Equity Classified Common Warrants D [Member]
Class of Stock [Line Items]
Number of shares for common warrants		50,933,271
Purchase Agreement [Member] \| Liability Classified Common Warrants C and D [Member]
Class of Stock [Line Items]
Number of shares for common warrants		30,147,810
Stock offering expenses		$ 900,000
Purchase Agreement [Member] \| Liability Classified Common Warrants D [Member]
Class of Stock [Line Items]
Proceeds from equity offerings		8,100,000
Sales Agreement [Member]
Class of Stock [Line Items]
Number of shares issued			4,050,000		2,530,000
Proceeds from equity offerings			$ 4,000,000	$ 6,300,000
Stock offering expenses		$ 2,300,000	500,000	700,000
Placement agent fees			$ 300,000	$ 500,000
Sales Agreement [Member] \| Alliance Global Partners [Member]
Class of Stock [Line Items]
Number of shares issued												1,000,000	9,100,000
Proceeds from equity offerings												$ 3,000,000	$ 85,300,000
Offering price per agreement								$ 320,000,000
Commission to agent								3.00%
Sales Agreement [Member] \| Pre-Funded Warrants [Member]
Class of Stock [Line Items]
Number of shares for common warrants			4,950,000		4,470,000							28,710,812			4,950,000
Price per share			$ 0.4999		$ 0.9999
Exercise price					$ 0.0001							$ 0.0001			$ 0.0001
Sales Agreement [Member] \| Common Warrants Series C [Member]
Class of Stock [Line Items]
Number of shares for common warrants												81,081,081
Exercise price												$ 0.555
Warrants term												2 years
Sales Agreement [Member] \| Common Warrants Series D [Member]
Class of Stock [Line Items]
Number of shares for common warrants												81,081,081
Exercise price												$ 0.85
Warrants term												5 years
Sales Agreement [Member] \| Common Warrants [Member]
Class of Stock [Line Items]
Number of shares for common warrants					7,000,000										18,000,000
Price per share					$ 1.00
Exercise price					$ 1.00										$ 0.50
Warrants term					5 years										5 years
Sales Agreement [Member] \| Common Warrants Series A [Member]
Class of Stock [Line Items]
Number of shares for common warrants			9,000,000
Exercise price			$ 0.50
Warrants term			5 years
Sales Agreement [Member] \| Common Warrants Series B [Member]
Class of Stock [Line Items]
Number of shares for common warrants			9,000,000
Price per share			$ 0.50
Exercise price			$ 0.50
Purchase Agreement with Lincoln Park 2022 [Member]
Class of Stock [Line Items]
Number of shares issued												100,000	200,000
Proceeds from equity offerings												$ 400,000	$ 500,000
Purchase Agreement with Lincoln Park 2022 [Member] \| Lincoln Park Capital Fund, LLC [Member]
Class of Stock [Line Items]
Number of shares issued						100,000
Commitment to purchase shares under agreement						$ 50,000,000
Number of shares issued, value						$ 1,000,000
Purchase Agreement With Lincoln Park [Member]
Class of Stock [Line Items]
Number of shares issued													500,000
Proceeds from equity offerings													$ 8,700,000
Percentage of issuance by issuer of common stock												19.99%
Maximum number of shares issued wIthout shareholder approval												500,000
Purchase Agreement With Lincoln Park [Member] \| Lincoln Park Capital Fund, LLC [Member]
Class of Stock [Line Items]
Number of shares issued							14,546
Commitment to purchase shares under agreement							$ 80,000,000
Number of shares issued, value							$ 1,600,000