Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY

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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
AOCI Attributable to Parent [Member]
Retained Earnings [Member]
Total
Beginning balance, value at Dec. 31, 2020 $ 6 $ 355,237 $ (62) $ (267,533) $ 87,648
Balance, at beginning (in shares) at Dec. 31, 2020 6,568,335        
Issuance of common stock in January 2021 ($25.60 per share), net of transactional expenses of $3,096 $ 2 36,902 36,904
Issuance of common stock in January 2021 ($25.60 per share), net of transactional expenses of $3,096 (in shares) 1,562,500        
Issuance of common stock in exchange for exercise of warrants in March 2021 ($18.24 per share) 2 2
Issuance of common stock in exchange for exercise of warrants in March 2021 ($18.24 per share) (in shares) 107        
Issuance of common stock in February 2021 ($38.40 per share), net of transactional expenses of $5,002 $ 2 64,995 64,997
Issuance of common stock in February 2021 ($38.40 per share), net of transactional expenses of $5,002 (in shares) 1,822,917        
Issuance of common stock under At-the-market offering, net of transactional expenses of $2,332 $ 4 69,288 69,292
Issuance of common stock under At-the-market offering, net of transactional expenses of $2,332 (in shares) 3,445,297        
Issuance of common stock under 2021 Purchase Agreement, net of transactional expenses of $75 $ 2 41,194 41,196
Issuance of common stock under 2021 Purchase Agreement, net of transactional expenses of $75 (in shares) 2,016,855        
Issuance of commitment shares under 2021 Purchase agreement
Issuance of commitment shares under 2021 Purchase agreement (in shares) 40,000        
Issuance of common stock in the acquisition of the OyaGen license 3,000 3,000
Issuance of common stock in the acquisition of the OyaGen license (in shares) 86,010        
Issuance of commitment shares under Lincoln park Purchase agreement
Issuance of commitment shares under Lincoln park Purchase agreement (in shares) 90,909        
Employee stock purchase plan 96 96
Employee stock purchase plan (in shares) 5,344        
Stock-based compensation 7,899 7,899
Foreign currency transaction loss (30) (30)
Net loss (92,287) (92,287)
Ending balance, value at Dec. 31, 2021 $ 16 578,613 (92) (359,820) 218,717
Balance, at end (in shares) at Dec. 31, 2021 15,638,274        
Issuance of common stock under At-the-market offering, net of transactional expenses of $3,078 $ 56 85,237 85,293
Issuance of common stock under At-the-market offering, net of transactional expenses of $3,078 (in shares) 56,357,869        
Issuance of common stock under 2022 Purchase Agreement $ 1 487 488
Issuance of common stock under 2022 Purchase Agreement (in shares) 1,000,000        
Issuance of common stock under 2021 Purchase Agreement $ 3 8,679 8,682
Issuance of common stock under 2021 Purchase Agreement (in shares) 2,853,480        
Issuance of commitment shares under 2022 Purchase agreement
Issuance of commitment shares under 2022 Purchase agreement (in shares) 625,000        
Preferred stock deemed dividend (6,659) (6,659)
Employee stock purchase plan 40 40
Employee stock purchase plan (in shares) 4,033        
Stock-based compensation 10,914 10,914
Foreign currency transaction loss (75) (75)
Net loss (110,218) (110,218)
Ending balance, value at Dec. 31, 2022 $ 76 $ 677,311 $ (167) $ (470,038) $ 207,182
Balance, at end (in shares) at Dec. 31, 2022 76,478,656