Annual report [Section 13 and 15(d), not S-K Item 405]

ASSET PURCHASE AGREEMENT WITH UPSHER-SMITH (Details Narrative)

v3.25.1
ASSET PURCHASE AGREEMENT WITH UPSHER-SMITH (Details Narrative) - USD ($)
 1 Months Ended 12 Months Ended
Jun. 30, 2023
Apr. 30, 2024
Dec. 31, 2024
Dec. 31, 2023
Business Acquisition [Line Items]        
Non-cash impairment charge, intangible assets     $ 9,200,000  
Intangible assets     120,000 $ 9,743,000
Revenue     10,094,000 7,768,000
Net loss     130,036,000 116,658,000
Developed technology - Zembrace [Member]        
Business Acquisition [Line Items]        
Non-cash impairment charge, intangible assets     6,200,000  
Developed technology - Tosymra [Member]        
Business Acquisition [Line Items]        
Non-cash impairment charge, intangible assets     3,000,000  
Tosymra and Zembrace [Member]        
Business Acquisition [Line Items]        
Intangible assets     0  
Tosymra [Member]        
Business Acquisition [Line Items]        
Revenue     1,548,000 1,464,000
Zembrace Symtouch [Member]        
Business Acquisition [Line Items]        
Revenue     8,546,000 6,304,000
Upsher-Smith Laboratories, LLC [Member]        
Business Acquisition [Line Items]        
Purchase price to be allocated $ 26,522,000      
Transition services monthly base fees, first six months 100,000      
Transition services monthly base fees, months seven through nine 150,000      
Transition services additional monthly fees 150,000      
Cash consideration $ 23,500,000 $ 3,000,000    
Pro forma net product sales       15,400,000
Pro forma net loss       $ 119,900,000
Revenue     10,100,000  
Net loss     $ 17,400,000  
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage reduction upon entry of generic product 66.70%      
Additional royalty percentage 3.00%      
Additional royalty percentage for U.S. patent 3.00%      
Additional royalty payment period 15 years      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 1 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 4.00%      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 1 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 0      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 1 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 30,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 2 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 7.00%      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 2 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 30,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 2 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 75,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 3 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 9.00%      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 3 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 75,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 3 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 100,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 4 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 12.00%      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 4 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 100,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 4 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 150,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 5 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 15.00%      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Earn-Out Range 5 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 150,000,000      
Upsher-Smith Laboratories, LLC [Member] | Tosymra [Member] | Sales Milestones [Member]        
Business Acquisition [Line Items]        
Maximum payment for sales milestones $ 15,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage reduction upon entry of generic product 90.00%      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 1 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 3.00%      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 1 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 0      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 1 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 30,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 2 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 6.00%      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 2 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 30,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 2 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 75,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 3 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 12.00%      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 3 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 75,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 3 [Member] | Maximum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 100,000,000      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 4 [Member]        
Business Acquisition [Line Items]        
Earm-out payment percentage 16.00%      
Upsher-Smith Laboratories, LLC [Member] | Zembrace Symtouch [Member] | Earn-Out Range 4 [Member] | Minimum [Member]        
Business Acquisition [Line Items]        
Earm-out net sales $ 100,000,000